In cases where Trusted RFCs are not working, the easiest solution is to delete the trusted relationship and re-build it. However, before doing that, please make sure that you have SAP Note 1491645 implemented in both systems of the trusting relationship.
- Delete the affected destinations in SM59 and SMT1.
- Re-create the trusted relationship:
- Refer to SAP Note 128447 and the mentioned guide there:
NOTE: Make sure that user being used to re-create the trusted relationship has enough authorization. Even if user has SAP_ALL, notice that S_RFC and S_RFCACL authorizations are also required.
I hope this helps.
Guilherme de Oliveira.